NRF2 and ATM(ataxia melangecsia?)

http://scholar.google.com/scholar?q=Atm+NRF2&hl=en&lr=&btnG=Search

Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δFind It @ MUgroup of 6 »
B Li, X Wang, N Rasheed, Y Hu, S Boast, T Ishii, K … – Genes & Development, 2004 – genesdev.org
The compromised accumulation of Nrf2 in Atm-deficient cells, a master transcription
factor for antioxidant gene expression, may be the reason that these cells
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Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C
B Li, X Wang, N Rasheed, Y Hu, S Boast, T Ishii, K … – GENES & DEVELOPMENT, 1824 – spahs.umt.edu
The compromised accumulation of Nrf2 in Atm-deficient cells, a master transcription
factor for antioxidant gene expression, may be the reason that these cells
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Activation of ATM by DNA strand break-inducing agents correlates closely with the number of DNA …group of 3 »
IH Ismail, S Nyström, J Nygren, O Hammarsten – Journal of Biological Chemistry – jbc.org
replication fork collapse or Nrf2-mediated signals to occur (40). We also found
that cells treated with CLM activated ATM to a higher extent
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Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased …Find It @ MUgroup of 3 »
N Rasheed, X Wang, QT Niu, J Yeh, B Li – Human Molecular Genetics, 2006 – hmg.oxfordjournals.org
This could be attributed to the failure of Atm –/– cells to up-regulate antioxidant
proteins through the transcription factor, Nrf2 (15 Go).
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Effects of Chrisotherapeutic Gold Compounds on Prostaglandin E 2 ProductionFind It @ MUgroup of 2 »
M Yamashita, K Ohuchi, M Takayanagi – Current Drug Targets-Inflammation & Allergy, 2003 – ingentaconnect.com
M of AF, 100- 500 µM of ATG, and 25-100 µM of ATM induced antioxidative of the anti-
oxidative transcription factor NF-E 2 -related factor 2 (Nrf2) which was
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Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage proteinFind It @ MUgroup of 3 »
T Ishii, M Yamada, H Sato, M Matsue, S Taketani, K … – Journal of Biological Chemistry, 1993 – jbc.org
KI Nakayama, and SP Goff Distinct roles of c-Abl and Atm in oxidative K. Sekizawa,
K. Uchida, and M. Yamamoto Transcription Factor Nrf2 Regulates Inflammation
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Signaling Pathways and Intracellular Targets of Sulforaphane Mediating Cell Cycle Arrest and …group of 2 »
L Gamet-Payrastre – Current Cancer Drug Targets, 2006 – ingentaconnect.com
the activation of a basic leucine zipper transcription factor, Nrf2 [6]. These to
inhibit cdc2 kinase activity through the activation of the ATM kinase, which
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The seventh Korea–Japan joint symposium on cancer and ageing research: molecular targets in cancer …Find It @ MUgroup of 2 »
SC Park, IK Lim, GY Koh, YJ Surh, YS Lee, H Fujiki … – Journal of Cancer Research and Clinical Oncology, 2006 – Springer
stitutive capacity of ATM-/- HSCs, indicating the important role of ATM in HSC Nrf2,
another redox-sensitive transcription fac- tor, plays a crucial role in
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Activation of Ataxia Telangiectasia Mutated by DNA Strand Break-inducing Agents Correlates Closely …Find It @ MUgroup of 3 »
IH Ismail, S Nyström, J Nygren, O Hammarsten – Journal of Biological Chemistry, 2005 – jbc.org
A previous report (39) shows that ATM is activated in response to oxidative secondary
events such as DNA-replication fork collapse or Nrf2-mediated signals to
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BRCA1 regulation of transcriptionFind It @ MUgroup of 3 »
EM Rosen, S Fan, Y Ma – Cancer Letters, 2006 – Elsevier
one model, DNA damage causes BRCA1 phosphorylation (mediated by ATM, ATR, CHK2 the
activity of the antioxidant transcription factor NFE2L2 (Nrf2) and protected
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Pathways of Induction of Peroxiredoxin I Expression in OsteoblastsROLES OF p38 MITOGEN-ACTIVATED …Find It @ MUgroup of 5 »
B Li, T Ishii, CP Tan, JW Soh, SP Goff – Journal of Biological Chemistry, 2002 – jbc.org
Nrf2 interacts with the antioxidant responsive elements and regulates the expression
of those genes and SP Goff Distinct roles of c-Abl and Atm in oxidative
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Retrovirus-Induced Oxidative Stress with Neuroimmunodegeneration Is Suppressed by Antioxidant …Find It @ MUgroup of 2 »
Y Jiang, VL Scofield, M Yan, W Qiang, N Liu, AJ … – Journal of Virology, 2006 – jvi.asm.org
We have reported (i) that activation of the Nrf2 transcription factor and upregulation
of antioxidative defenses occurs in astrocytes infected with ts1 in
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A COMPARISON OF THE THEORETICAL AND EXPERIMENTAL STAGNATION-POINT HEAT TRANSFER INAN ARC-HEATED …
RD Brown – ntrs.nasa.gov
Page 1. NASATECHNICAL NOTE NASA c, I “. _.- ‘ TN D-19 – – 127 A COMPARISON OF THE
THEORETICAL AND EXPERIMENTAL STAGNATION-POINT HEAT TRANSFER INAN
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Mammalian Genetic Models With Minimal Or Complex PhenotypesFind It @ MUgroup of 3 »
C Zhang, T Moriguchi, M Kajihara, R Esaki, A … – Mol. Cell. Biol, 2005 – mcb.asm.org
Zhou, and Regina Brigelius-Flohé The GI-GPx Gene Is a Target for Nrf2 Mol Khanna,
Thomas Ludwig, and Tej K. Pandita Involvement of Human MOF in ATM Function Mol
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Hyperbaric Oxygen Reduces Acetaminophen Toxicity and Increases HIF-1 {alpha} ExpressionFind It @ MUgroup of 4 »
SD Salhanick, B Belikoff, D Orlow, D Holt, W … – Academic Emergency Medicine, 2006 – intl.aemj.org
and hamsters treated with APAP and HBO 2 at 2.8 atm abs for 90 High sensitivity of
Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased
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Hyperbaric Oxygen Reduces Acetaminophen Toxicity and Increases HIF-1a Expression
SD Salhanick, B Belikoff, D Orlow, D Holt, W … – Academic Emergency Medicine – aemj.org
HBO 2 administered at pressures of 3 atmos- pheres absolute (atm abs) produces arterial
oxygen ten- sions of up to 2,000 torr, and tissue O 2 tensions of 400
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Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal …Find It @ MUgroup of 3 »
J Bodo, J Jakubikova, I Chalupa, Z Bartosova, K … – Apoptosis, 2006 – Springer
proficient TK6 and -deficient MT1 cell lines as well as the influence of proteasomal
inhibitor MG132, caspase inhibitor Z-VAD-fmk, and ATM inhibitor caffeine
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Death at the Dead Seagroup of 2 »
S Bialik, T Gottlieb – nature.com
JNK, jun N-terminal kinase; NGF, nerve growth factor; Nrf2, NF-E2 This ATM (ataxia
telangiectasia mutated protein)-dependent phosphorylation was found not to
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c-Myc target gene specificity is determined by a post-DNAbinding mechanismgroup of 10 »
KE Boyd, J Wells, J Gutman, SM Bartley, PJ Farnham – 1998 – pnas.org
Abstract of this Article ( ). PDF Version of this Article. Similar articles found
in: PNAS Online ISI Web of Science PubMed. PubMed Citation.
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POSTER TOPIC PS4
R GTPases – blackwellpublishing.com
Two domains of Nrf2 cooperatively bind CREB binding protein and synergistically
activate transcription K. Itoh 1,2 , Y. Katoh 1 , E. Yoshida 3 , M. Miyagishi, A
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CHARACTERIZATION OF ADULT SPINAL CORD STEM/PROG-ENITOR CELLS FOLLOWING TRANSPLANTATION INTO FO-CAL …group of 2 »
A Mothe, I Kulbatski, C Tator – liebertonline.com
These re- sults suggest that strategies to augment Nrf2-mediated gene expression
anesthetized, intubated and underwent mod- erate (1.8-2.2atm) fluid percussion
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Enzyme Induction and Dietary Chemicals as Approaches to Cancer Chemoprevention: The Seventh DeWitt S …Find It @ MUgroup of 3 »
AH Conney – 2003 – cancerres.aacrjournals.org
The importance of Phase II enzymes for inactivating chemical carcinogens was
highlighted in a study with nrf2 transcription factor- deficient mice (103).
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RORA, a large common fragile site gene, is involved in cellular stress responsegroup of 3 »
Y Zhu, S McAvoy, R Kuhn, DI Smith – Oncogene, 2006 – nature.com
named NRF1 by the Nuclear Receptor Nomenclature Committee), RORB (NRF2) (Carlberg
et The deficiency of ATR, but not ATM (ataxia-telangiectasia mutated), caused
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Current World Literature
D Morioka, M Kasahara, Y Takada… – Current Opinion in Organ Transplantation, 2006 – co-transplantation.com
Gong PF, Cederbaum AI. Nrf2 is increased by CYP2E1 in rodent liver and HepG2
cells and protects against oxidative stress caused by CYP2E1.
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“Translating” Tumor Hypoxia: Unfolded Protein Response(UPR)-Dependent and UPR-Independent PathwaysFind It @ MUgroup of 3 »
C Koumenis, BG Wouters – Molecular Cancer Research, 2006 – mcr.aacrjournals.org
The second PERK-dependent pathway involves nuclear import of the Nrf2 transcription
factor following its dissociation from the cytoplasmic protein Keap1 (44).
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Effects of Heavy Metals on Mitogen-Activated Protein Kinase PathwaysFind It @ MUgroup of 4 »
M MATSUOKA, H IGISU – Environmental Health and Preventive Medicine, 2002 – J-STAGE
Page 1. 210 [Environmental Health and Preventive Medicine 6, 210–217, January
2002] Review Article Effects of Heavy Metals on Mitogen
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Many cuts to ruin: a comprehensive update of caspase substratesFind It @ MUgroup of 4 »
U Fischer, RU Jänicke, K Schulze-Osthoff – Cell Death and Differentiation, 2003 – nature.com
Inhibition of DNA repair, for instance by the cleavage of PARP-1 or the kinases
ATM and DNA-PK, has been long thought to promote the apoptosis process.
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Oxidative Stress Mediates Sodium Arsenite-Induced Expression of Heme Oxygenase-1, Monocyte …Find It @ MUgroup of 5 »
PC Lee, IC Ho, TC Lee – Toxicological Sciences, 2005 – toxsci.oxfordjournals.org
Similarly, iAs-induced Nrf2 nuclear accumulation is enhanced by copper (II)
3,5-diisopropyl salicylate hydrate, a cell-permeable SOD (Pi et al., 2003 ).
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The Yeast Ubiquitin Ligase SCFMet30 Regulates Heavy Metal ResponseFind It @ MUgroup of 5 »
JL Yen, NY Su, P Kaiser – Molecular Biology of the Cell, 2005 – molbiolcell.org
This in turn prevents ubiquitination of the transcription factor Nrf2, which
coordinates the transcriptional response to oxidative stress (Jaiswal, 2004 ).
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NO, Chemiluminescent Wake Radiation
RL SCHAPKER, M CAMAC – AIAA JOURNAL – pdf.aiaa.org
Page 1. 22.54 AIAA JOURNAL VOL. 7, NO. 12 NO, Chemiluminescent Wake Radiation
R ICHARD L. SCHAPKER” AND M ORTON CAMAC” AVGO Everett
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Anti-Aging Medicine LiteratureWatchgroup of 4 »
C Senescence – JOURNAL OF ANTI-AGING MEDICINE, 2001 – liebertonline.com
Trends Genet 2003;19:439–446. Chan SW, Blackburn EH. Telomerase and ATM/Tel1p protect
telomeres from nonhomologous end joining. Mol Cell 2003;11:1379–1387.
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Functional and physical communication between oncoproteins and tumor suppressorsgroup of 3 »
EV Prochownik – Cellular and Molecular Life Sciences (CMLS), 2005 – Springer
Page 1. CMLS, Cell. Mol. Life Sci. 62 (2005) DOI 10.1007/s00018-005-5199-8 © Birkhäuser
Verlag, Basel, 2005 CMLS Cellular and Molecular Life Sciences Review
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Subject Indexgroup of 4 »
DISM Behavior, ICMM Endothelial, O Synthase, I … – Circulation Research – circres.ahajournals.org
394 Telomeres and Cardiovascular Disease: Does Size Matter?, 575 ATM Human
Cytomegalovirus Mice Lacking CC-Chemokine Receptor-2, 671 CD36 Role of Nrf2 in the
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[BOOK] Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles
HJ Forman, M Torres, J Fukuto – 2003 – books.google.com
237 Hydroperoxides Lisa Landino 14 Phylogenetic Conservation ofthe Nrf2-Keap1
Signaling System 256 Xue Zhang, Mark Garfinkel, andDouglas Ruden
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Observations of Twelve USEPA Priority Polycyclic Aromatic Hydrocarbons in the Aitken Size Range (10 …Find It @ MUgroup of 4 »
AH Miguel, A Eiguren-Fernandez, C Sioutas, PM Fine … – Aerosol Science & Technology, 2005 – Taylor & Francis
Subcooled liquid vapor pressures (log p ◦ L ) are in atm at 25 ◦ C Nrf2 is a Key
Transcription Factor that Regulates Antioxidant Defense in Macrophages and
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Induction of c-fos Proto-oncogene in Mesangial Cells by CadmiumFind It @ MUgroup of 4 »
Z Wang, DM Templeton – Journal of Biological Chemistry, 1998 – jbc.org
Institution: Google Indexer Sign In as Member/Non-Member.
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EDUCATIONAL SESSION 2: THE ROLE OF APOPTOSIS IN THE PATHOGENESIS OF CANCERgroup of 4 »
Ma Reality – aacr.org
Members of the bZIP transcription factor, Nrf2, which is released by Keap1 in the
cytosol upon “chemical stress”, translocates to the nucleus and
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Thermal conductivity coefficients of water and heavy water in the liquid state up to 370. degree. CFind It @ MU
B Le Neindre, P Bury, R Tufeu, B Vodar – Journal of Chemical and Engineering Data, 1976 – pubs.acs.org
Ziebland and Burton, using a coaxial cylinder apparatus, studied temperatures ranging
between 75 and 260 OC and pressures from 24 to 294 atm ( 78).
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ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27kip1 Expression via the Akt-FOXO3a …Find It @ MUgroup of 5 »
Y Hu, X Wang, L Zeng, DY Cai, K Sabapathy, SP Goff … – Molecular Biology of the Cell, 2005 – molbiolcell.org
Institution: Google Indexer Sign In as Member. Originally published as
MBC in Press, 10.1091/mbc.E05-04-0301 on June 1, 2005 Vol.
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Current World LiteratureFind It @ MU
AM AlSendi, P Shetty, AO Musaiger… – Current Opinion in Lipidology, 2005 – co-lipidology.com
February 2005, 16:1 > Current World Literature.
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32 ndannual meeting of the American Aging Association, 17 thannual meeting of the American College …Find It @ MU
M Baltimore – AGE, 2003 – Springer
Page 1. 32 “d ANNUAL MEETING OF THE AMERICAN AGING ASSOCIATION I”Ph ANNUAL
MEETING OF THE AMERICAN COLLEGE OF CLINICAL GERONOTOLOGY
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GBM annual fall meeting
NI Mice – wissenschaft-online.de
Page 1. GBM annual fall meeting Berlin/Potsdam September 18-21, 2005 Abstracts
Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22
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Role of Nitric Oxide in Cardiovascular Adaptation to Intermittent HypoxiaFind It @ MUgroup of 2 »
EB Manukhina, HF Downey, RT Mallet – 2006 – ebmonline.org
in which the average intercapillary distance decreased from ~50 to ~40 µM after
3 weeks of hypobaric hypoxia at a pressure of 380 torr (0.5 atm, equivalent to
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